Corsantrum Technology

iva-caftor/teza-caftor/elexa-caftor is a triple-combination prescription medication used for the long-term treatment of cystic fibrosis (CF). It targets the underlying cause of CF by improving the function and amount of the CFTR protein on cell surfaces.

Uses

iva-caftor/teza-caftor/elexa-caftor is indicated for patients aged 2 years and older who have at least one F508del mutation in the CFTR gene. It is typically used in combination with another medicine, ivacaftor (Kalydeco).

How to Take It

·        Correct administration is critical for the drug's effectiveness:

·        Schedule: Usually taken twice daily, about 12 hours apart.

·        Morning: Take two Kaftrio combination tablets.

·        Evening: Take one ivacaftor-only tablet.

·        With Food: Must be taken with fat-containing food (e.g., eggs, cheese, whole milk, meat, or food prepared with butter/oils) to ensure proper absorption.

·        Method:

·        Tablets: Swallow whole. Do not crush, chew, or break.

·        Granules (for children): Mix the entire sachet into one teaspoon (5 mL) of soft food or liquid (e.g., yogurt, juice) at or below room temperature. Consume within one hour.

·        Precautions: Avoid grapefruit or grapefruit juice, as it can increase side effects.

Side Effects

·        Side effects can range from common to more serious medical concerns:

·        Very Common (≥1 in 10): Headache, dizziness, upper respiratory tract infections (common cold), diarrhoea, stomach pain, and rash (more frequent in women and children).

·        Liver Problems: Increased liver enzymes are very common. Watch for yellowing of skin/eyes (jaundice), dark urine, or upper right stomach pain.

·        Psychological Effects: Infrequent reports of depression, anxiety, sleep disturbance, or behavioural changes (especially in children 2–5 years old), typically occurring within the first three months of treatment.

·        Eye Health: Some children/adolescents may develop cloudiness of the eye lens (cataracts); regular eye exams may be recommended.

Product Introduction

Evermil 10 Tablet is used for the prevention of organ rejection in transplant patients. It regulates the body’s immune response, so the body can accept the new organ. It is also used in combination with other medicines to treat cancers of breast, pancreas, lungs, and kidney.

Evermil 10 Tablet must be taken in a dose and duration as per the prescription. It can be taken with or without food but make sure to take it at about the same time every day. An overdose of this medicine may have serious side effects on the body.

The common side effects of this medicine include infection, fever, cough, fatigue, diarrhea, and upper respiratory infection. If any of the side effects persist or bother you, consult the doctor immediately. Inform the doctor immediately if you experience any allergic reactions (rash, shortness of breath, coughing, swelling, etc.). Always seek medical advice if you have increased thirst or increased frequency of urination, suffer from shortness of breath, cough or fever, or need to receive any vaccination after taking this medication.

Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you for some laboratory tests to know the effects of the medicine in the body. It may affect male or female fertility, so consult the doctor if you are planning to have a child.

Uses Of Evermil Tablet

Prevention of organ rejection in transplant patients

Benefits Of Evermil Tablet

In Prevention of organ rejection in transplant patients

Evermil 10 Tablet is used with other medications to prevent organ transplant rejection. Rejection usually happens due to attack by the immune system of the person receiving the transplanted organ on the transplant itself, in people who are receiving any organ transplants, like kidney, liver, heart etc. This medicine reduces the activity of a person's own immune system and prevents any such rejection.

Side Effects Of Evermil Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common Side Effects Of Evermil

Infection

Fever

Cough

Fatigue

Diarrhea

Upper respiratory tract infection

How To Use Evermil Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Evermil 10 Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Evermil Tablet Works

Evermil 10 Tablet suppresses the activity of body's immune system and prevents rejection of the transplanted organ.

Product introduction

Siromus 1mg Tablet is used for prevention of organ rejection in transplant patients. It regulates the body’s immune response, so the body can accept the new organ.

Siromus 1mg Tablet must be taken in a dose and duration as per the prescription. It can be taken with or without food but make sure to take it at about the same time every day. An overdose of this medicine may have serious side effects on the body.

Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you for some laboratory tests to know the effects of the medicine in the body. If you notice signs of infection, any changes in the appearance or size of a mole, unusual growths or lumps, or unusual tiredness or weakness during the treatment, you must consult the doctor immediately.

Uses of Siromus Tablet

Prevention of kidney transplant rejection

Benefits of Siromus Tablet

In Prevention of kidney transplant rejection

Siromus 1mg Tablet is used with other medications to prevent kidney transplant rejection. Rejection usually happens due to attack by the immune system of the person receiving the transplanted organ on the transplant itself, in people who are receiving kidney transplants. This medicine reduces the activity of a person's own immune system and prevents any such rejection.

Side effects of Siromus Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Siromus

Nausea

Increased blood lipid level

Low blood platelets

Headache

Abdominal pain

Fever

Anemia (low number of red blood cells)

Urinary tract infection

Diarrhea

High blood pressure

Joint pain

Edema (swelling)

How to use Siromus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Siromus 1mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Siromus Tablet works

Siromus 1mg Tablet is an immunosuppressant. It works by suppressing your body’s immune response following transplant of an organ (eg. liver, kidney, heart). This helps your body to accept the new organ as if it were your own.

Safety advice

Alcohol

It is not known whether it is safe to consume alcohol with Siromus 1mg Tablet.

Pregnancy

Siromus 1mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

Breast feeding

Siromus 1mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

Siromus 1mg Tablet does not usually affect your ability to drive.

Kidney

Siromus 1mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Siromus 1mg Tablet is recommended.

Liver

Siromus 1mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Siromus 1mg Tablet may be needed.

Dose adjustment is not recommended in patients with mild to moderate liver disease.

Product introduction

SiroBoon 1mg Tablet is used for prevention of organ rejection in transplant patients. It regulates the body’s immune response, so the body can accept the new organ.

SiroBoon 1mg Tablet must be taken in a dose and duration as per the prescription. It can be taken with or without food but make sure to take it at about the same time every day. An overdose of this medicine may have serious side effects on the body.

Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you for some laboratory tests to know the effects of the medicine in the body. If you notice signs of infection, any changes in the appearance or size of a mole, unusual growths or lumps, or unusual tiredness or weakness during the treatment, you must consult the doctor immediately.

Uses of SiroBoon Tablet

Prevention of kidney transplant rejection

Benefits of SiroBoon Tablet

In Prevention of kidney transplant rejection

SiroBoon 1mg Tablet is used with other medications to prevent kidney transplant rejection. Rejection usually happens due to attack by the immune system of the person receiving the transplanted organ on the transplant itself, in people who are receiving kidney transplants. This medicine reduces the activity of a person's own immune system and prevents any such rejection.

Side effects of SiroBoon Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Siromus

Nausea

Increased blood lipid level

Low blood platelets

Headache

Abdominal pain

Fever

Anemia (low number of red blood cells)

Urinary tract infection

Diarrhea

High blood pressure

Joint pain

Edema (swelling)

How to use SiroBoon Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. SiroBoon 1mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How SiroBoon Tablet works

SiroBoon 1mg Tablet is an immunosuppressant. It works by suppressing your body’s immune response following transplant of an organ (eg. liver, kidney, heart). This helps your body to accept the new organ as if it were your own.

 Safety advice

Alcohol

It is not known whether it is safe to consume alcohol with SiroBoon 1mg Tablet.

Pregnancy

SiroBoon 1mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

Breast feeding

SiroBoon 1mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SiroBoon 1mg Tablet does not usually affect your ability to drive.

Kidney

SiroBoon 1mg Tablet is safe to use in patients with kidney disease. No dose adjustment of SiroBoon 1mg Tablet is recommended.

Liver

SiroBoon 1mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of SiroBoon 1mg Tablet may be needed.

Dose adjustment is not recommended in patients with mild to moderate liver disease.

Product introduction

SiroBoon 2mg Tablet is used for prevention of organ rejection in transplant patients. It regulates the body’s immune response, so the body can accept the new organ.

SiroBoon 2mg Tablet must be taken in a dose and duration as per the prescription. It can be taken with or without food but make sure to take it at about the same time every day. An overdose of this medicine may have serious side effects on the body.

Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you for some laboratory tests to know the effects of the medicine in the body. If you notice signs of infection, any changes in the appearance or size of a mole, unusual growths or lumps, or unusual tiredness or weakness during the treatment, you must consult the doctor immediately.

Uses of SiroBoon Tablet

Prevention of kidney transplant rejection

Benefits of SiroBoon Tablet

In Prevention of kidney transplant rejection

SiroBoon 2mg Tablet is used with other medications to prevent kidney transplant rejection. Rejection usually happens due to attack by the immune system of the person receiving the transplanted organ on the transplant itself, in people who are receiving kidney transplants. This medicine reduces the activity of a person's own immune system and prevents any such rejection.

Side effects of SiroBoon Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Siromus

Nausea

Increased blood lipid level

Low blood platelets

Headache

Abdominal pain

Fever

Anemia (low number of red blood cells)

Urinary tract infection

Diarrhea

High blood pressure

Joint pain

Edema (swelling)

How to use SiroBoon Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. SiroBoon 2mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How SiroBoon Tablet works

SiroBoon 2mg Tablet is an immunosuppressant. It works by suppressing your body’s immune response following transplant of an organ (eg. liver, kidney, heart). This helps your body to accept the new organ as if it were your own.

Safety advice

Alcohol

It is not known whether it is safe to consume alcohol with SiroBoon 2mg Tablet.

Pregnancy

SiroBoon 2mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

Breast feeding

SiroBoon 2mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SiroBoon 2mg Tablet does not usually affect your ability to drive.

Kidney

SiroBoon 2mg Tablet is safe to use in patients with kidney disease. No dose adjustment of SiroBoon 2mg Tablet is recommended.

Liver

SiroBoon 2mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of SiroBoon 2mg Tablet may be needed.

Dose adjustment is not recommended in patients with mild to moderate liver disease.

Product introduction

SiroBoon 5mg Tablet is used for prevention of organ rejection in transplant patients. It regulates the body’s immune response, so the body can accept the new organ.

SiroBoon 5mg Tablet must be taken in a dose and duration as per the prescription. It can be taken with or without food but make sure to take it at about the same time every day. An overdose of this medicine may have serious side effects on the body.

Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you for some laboratory tests to know the effects of the medicine in the body. If you notice signs of infection, any changes in the appearance or size of a mole, unusual growths or lumps, or unusual tiredness or weakness during the treatment, you must consult the doctor immediately.

Uses of SiroBoon Tablet

Prevention of kidney transplant rejection

Benefits of SiroBoon Tablet

In Prevention of kidney transplant rejection

SiroBoon 5mg Tablet is used with other medications to prevent kidney transplant rejection. Rejection usually happens due to attack by the immune system of the person receiving the transplanted organ on the transplant itself, in people who are receiving kidney transplants. This medicine reduces the activity of a person's own immune system and prevents any such rejection.

Side effects of SiroBoon Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Siromus

Nausea

Increased blood lipid level

Low blood platelets

Headache

Abdominal pain

Fever

Anemia (low number of red blood cells)

Urinary tract infection

Diarrhea

High blood pressure

Joint pain

Edema (swelling)

How to use SiroBoon Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. SiroBoon 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How SiroBoon Tablet works

SiroBoon 5mg Tablet is an immunosuppressant. It works by suppressing your body’s immune response following transplant of an organ (eg. liver, kidney, heart). This helps your body to accept the new organ as if it were your own.

Safety advice

Alcohol

It is not known whether it is safe to consume alcohol with SiroBoon 5mg Tablet.

Pregnancy

SiroBoon 5mg Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you.

Breast feeding

SiroBoon 5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

SiroBoon 5mg Tablet does not usually affect your ability to drive.

Kidney

SiroBoon 5mg Tablet is safe to use in patients with kidney disease. No dose adjustment of SiroBoon 5mg Tablet is recommended.

Liver

SiroBoon 5mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of SiroBoon 5mg Tablet may be needed.

Dose adjustment is not recommended in patients with mild to moderate liver disease.

Product Introduction

Pangraf 2 Capsule is used along with other medicines to prevent your body from rejecting a new organ (e.g., liver, kidney, or heart) after transplant. It does so by weakening your body’s immune system, so it does not attack the new organ. This medication belongs to a class of drugs known as immunosuppressants.

The amount of Pangraf 2 Capsule you take and how often you take it depends on the type of transplant you have, your body weight, and what other medicines you are taking. Follow your doctor’s instructions carefully. You should take it on an empty stomach, at least 1 hour before or 2 hours after a meal. Take this medicine regularly to get the maximum benefit and keep taking it, even if you feel well. If you stop taking it, you may increase the chances of rejecting your transplanted organ.

Pangraf 2 Capsule has many potential side effects. It can cause or worsen diabetes and kidney problems. These need urgent medical attention. Other common side effects include tremor, infections, high blood pressure, and insomnia. If the side effects do not go away or get worse, tell your doctor. Pangraf 2 Capsule lowers your immune system making you susceptible to catching more infections than usual.

Before taking this medicine, tell your doctor if you have kidney, liver, or heart problems, diabetes, or high blood pressure. Also let your doctor know what other medications you are taking, especially for infections, pain, and arthritis. These and others may affect, or be affected by, this medicine. You should limit your exposure to the sun and UV (ultraviolet) light while taking it because immunosuppressants could increase your risk of skin cancer.

Both men and women using this medicine should use effective birth control to prevent pregnancy. This medicine is not normally recommended during pregnancy or while breastfeeding unless it is clearly needed. Before and during treatment you will need frequent medical tests to monitor your progress, and your blood pressure will need to be checked often.

Uses Of Pangraf Capsule

Prevention of organ rejection in transplant patients

Benefits Of Pangraf Capsule

In Prevention of organ rejection in transplant patients

Pangraf 2 Capsule belongs to a group of medicines known as immunosuppressants. Organ rejection happens when your immune system treats the new organ as an invader and attacks it. This medicine weakens your immune response (which usually fights infection) and reduces the chance of your body attacking the transplanted organ. It is used in combination with other medicines to make it much more likely that your transplant operation will be successful. You should continue taking the medicine and should not stop it until your doctor says so.

Side Effects Of Pangraf Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common Side Effects Of Pangraf

Increased glucose level in blood

Kidney damage

Insomnia (difficulty in sleeping)

Tremors

High blood pressure

Infection

How To Use Pangraf Capsule

Take this medicine in the dose and duration as advised by your doctor. Pangraf 2 Capsule is to be taken empty stomach.

How Pangraf Capsule Works

Pangraf 2 Capsule is an immunosuppressant. It works by suppressing your body’s immune response following the transplant of an organ (e.g., liver, kidney, heart). This helps your body to accept the new organ as if it were your own.