Corsantrum Technology

What Is Mavenclad (Cladribine) For?

Mavenclad (cladribine) is a an oral nucleoside analog of deoxyadenosine indicated for the treatment people with relapsing forms of multiple sclerosis. Cladribine is used in patients whose disease is highly active.

The active ingredient cladribine is approved in the EU, USA, and TGA, among others as an intravenous infusion for the treatment of certain leukemias (cancers affecting lymphocytes). 

Uses Of Macitent Tablet

In MS the patient’s immune system attacks and damages the protective sheath around the nerve cells in the central nervous system (the brain and spinal cord), impairing the communication between neurons which ultimately results in the neurons' death.

The immune cells called lymphocytes play a key role in this process

The active substance in Mavenclad, cladribine, is a nucleoside analog of deoxyadenosine, meaning that it has a similar chemical structure to one of the substances needed to make up the DNA (purine). In the body, cladribine is taken up by cells such as lymphocytes and therein interferes with the production of new DNA. This leads to the death of the lymphocytes, slowing down the progression of multiple sclerosis.

Where Has Mavenclad (Cladribine) Been Approved?

Mavenclad (cladribine) was approved for relapsing forms of multiple sclerosis by:

• European Medical Agency (EMA), European Union, August 22, 2017
• Therapeutic Goods Administration (TGA), Australia, July 17, 2017
• Health Canada on November 29, 2017
• Food and Drug Administration (FDA), US, March 29, 2019
• Medsafe, New Zealand, August 1, 2019
• Please note that this medicine may have also been approved in other regions than the ones we’ve listed. If you have a question about its approval in a specific country feel free to contact our support team.

How is Mavenclad (cladribine) taken?

The standard dosage is :

• Cumulative dose of 3.5 mg/kg body weight over 2 years, administered as 1 treatment course of 1.75 mg/kg per year.
• In year 1 and year 2 each treatment course consists of 2 treatment weeks, one at the beginning of the first month and one at the beginning of the second month of the respective treatment year.
• Each treatment week consists of 4 or 5 days on which a patient receives 10 mg or 20 mg (one or two tablets) as a single daily dose, depending on body weight.
• Following completion of the 2 treatment courses (after year 2), no further cladribine treatment is required in years 3 and 4. Re-initiation of therapy after year 4 has not been studied.

Are there any known adverse reactions or side effects of Mavenclad (cladribine)?

Common adverse reactions

The most common adverse reactions listed in the prescribing information include:

• herpes
• lymphopenia: low lymphocytes count
• neutropenia: decrease in neutrophil count
• rash
• alopecia.

Serious adverse reactions

The serious adverse reactions listed in the prescribing information include:

• lymphopenia: low lymphocytes count.

Use in a specific population

As Mavenclad (cladribine) can be fatal for a fetus, it is not advised for women who are pregnant or breastfeeding. Breastfeeding is contraindicated during treatment and for 1 week after the last dose.

Avoid use in patients with a compromised immune system as effects on lymphocytes reduce the body’s immune defence against infections and cancer. It must not be given to patients with active cancers.

• Ovarian cancer
• Cervical cancer
• Testicular cancer

Introduction :

Docetere 20mg Injection is an anti-cancer medication used for the treatment of breast cancer, non-small cell lung cancer, prostate cancer and cancers of head and neck.

Docetere 20mg Injection is given as an injection by a qualified medical professional. Your doctor will determine the appropriate dosage and frequency of administration for you. This is based on the condition you are being treated for and is subject to change. You should follow your doctor's instructions to the letter. It can have potentially dangerous negative effects if taken improperly or in excess. The benefits might not become apparent to you for a few weeks or months, but you shouldn't stop taking it until your doctor instructs you to.

Some of the common side effects of this medicine include breathlessness, constipation, edema (swelling), infection, loss of appetite, muscle pain, nail disorder, pain, and weakness. To reduce these side effects your doctor may suggest some medication along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function. Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.


Uses :

• Breast cancer
• Non-small cell lung cancer
• Prostate cancer
• Cancer of head and neck

Introduction :

Docetax 120 Mg Injection is an anti-cancer medication used for the treatment of breast cancer, non-small cell lung cancer, prostate cancer and cancers of head and neck.

Docetax 120 Mg Injection is given as an injection by a qualified medical professional. Your doctor will determine the appropriate dosage and frequency of administration for you. This is based on the condition you are being treated for and is subject to change. You should follow your doctor's instructions to the letter. It can have potentially dangerous negative effects if taken improperly or in excess. The benefits might not become apparent to you for a few weeks or months, but you shouldn't stop taking it until your doctor instructs you to.

Some of the common side effects of this medicine include breathlessness, constipation, edema (swelling), infection, loss of appetite, muscle pain, nail disorder, pain, and weakness. To reduce these side effects your doctor may suggest some medication along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function. Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.


Uses :

• Breast cancer
• Non-small cell lung cancer
• Prostate cancer
• Cancer of head and neck

Introduction :

Docetax 80 Mg / 2 Ml Injection is an anti-cancer medication used for the treatment of breast cancer, non-small cell lung cancer, prostate cancer and cancers of head and neck.

Docetax 80 Mg / 2 Ml Injection is given as an injection by a qualified medical professional. Your doctor will determine the appropriate dosage and frequency of administration for you. This is based on the condition you are being treated for and is subject to change. You should follow your doctor's instructions to the letter. It can have potentially dangerous negative effects if taken improperly or in excess. The benefits might not become apparent to you for a few weeks or months, but you shouldn't stop taking it until your doctor instructs you to.

Some of the common side effects of this medicine include breathlessness, constipation, edema (swelling), infection, loss of appetite, muscle pain, nail disorder, pain, and weakness. To reduce these side effects your doctor may suggest some medication along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function. Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.


Uses :

• Breast cancer
• Non-small cell lung cancer
• Prostate cancer
• Cancer of head and neck

Introduction :

Taxotere 20mg Injection is an anti-cancer medication used for the treatment of breast cancer, non-small cell lung cancer, prostate cancer and cancers of head and neck.

Taxotere 20mg Injection is given as an injection by a qualified medical professional. Your doctor will determine the appropriate dosage and frequency of administration for you. This is based on the condition you are being treated for and is subject to change. You should follow your doctor's instructions to the letter. It can have potentially dangerous negative effects if taken improperly or in excess. The benefits might not become apparent to you for a few weeks or months, but you shouldn't stop taking it until your doctor instructs you to.

Some of the common side effects of this medicine include breathlessness, constipation, edema (swelling), infection, loss of appetite, muscle pain, nail disorder, pain, and weakness. To reduce these side effects your doctor may suggest some medication along with it. But, inform your doctor if you notice unexplained bruising or bleeding, sore throat, mouth ulcers, high temperature (fever). This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells and liver function. Your doctor may get regular blood tests done to monitor your blood cells and liver function during treatment with this medicine.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.


Uses :

• Breast cancer
• Non-small cell lung cancer
• Prostate cancer
• Cancer of head and neck

Benefits :

In Breast cancer :

Taxotere 20mg Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It alleviates breast cancer symptoms such breast lumps, bloody nipple discharge, or changes in the breast's form or texture. Taxotere 20mg Injection destroys cancer cells, inhibits their growth, and stops them from proliferating. If you have any concerns about any of the adverse effects, talk to your doctor.

In Non-small cell lung cancer :

Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Taxotere 20mg Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

In Prostate cancer :

Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Taxotere 20mg Injection decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.


Side Effects :

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

Introduction :

Breast cancer, pancreatic cancer, and non-small cell lung cancer are all treated with the anti-cancer drug Paclitax Nab 100 Mg Injection.

It is given as an injection by a qualified medical professional. Your doctor will determine the appropriate dosage and frequency of administration for you. This is based on the condition you are being treated for and is subject to change. You should follow your doctor's instructions to the letter. It can have potentially dangerous negative effects if taken improperly or in excess. The benefits might not become apparent to you for a few weeks or months, but you shouldn't stop taking it until your doctor instructs you to.

This medication frequently causes nausea, vomiting, and weakness as adverse effects. Serious side effects like hand and lip swelling, hair loss, and weight gain are also possible. Your doctor might advise taking additional medicine in addition to this to lessen these negative effects. But if you experience unusual bleeding or bruises, a sore throat, oral ulcers, or a high temperature, call your doctor right once (fever). Your blood's red and white blood cell counts could drop as a result of this medication, making you more susceptible to infections. You must have routine blood tests to monitor the health of your liver and blood cells.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.


Uses :

Breast cancer

Non-small cell lung cancer

Pancreatic cancer


Side Effects :

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

Common side effects of Paclitax Nab :

• Nausea
• Vomiting
• Weakness
• Low blood platelets
• Rash
• Upper respiratory tract infection
• Urinary tract infection
• Bleeding
• Anemia (low number of red blood cells)
• Flushing (sense of warmth in the face, ears, neck and trunk)
• Hair loss
• Decreased blood pressure
• Peripheral neuropathy (tingling and numbness of feet and hand)
• Diarrhea
• Decreased white blood cell count (neutrophils)

Introduction :

Erubin 50mg Injection is used in the treatment of various types of cancers of blood, breast, lung, ovaries and soft tissues. It can be administered alone or occasionally in conjunction with other drugs as part of chemotherapy.

It is administered carefully by a licenced medical expert as a drip or infusion vein. Your doctor will determine the appropriate dosage and frequency of administration for you. This is based on the condition you are being treated for and is subject to change. You should follow your doctor''s instructions to the letter. It can have potentially dangerous negative effects if taken improperly or in excess.It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to both male and female to use reliable contraception during the treatment.

The most common side effects of this medicine include vomiting, allergic reaction, nausea, mouth sore, and hair loss.  If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Infections can sometimes be life-threatening. Regular blood tests are required to monitor your blood cells along with the kidney, liver, and heart function during treatment with this medicine.

Before taking this medicine, tell your doctor if you have severe liver or heart-related problems, or if you are pregnant, or breastfeeding.  Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.


Uses :

Cancer


Benefits :

For cancer:

Erubin 50mg Injection helps to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. Adrim 50mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. You should talk to your doctor about the advantages and disadvantages of this powerful and extremely poisonous medication. While receiving this medication, you should abstain from alcohol consumption and consume lots of water to stay hydrated.


Side Effects :

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

Common side effects of Erubin :

• Vomiting
• Allergic reaction
• Nausea
• Mouth sore
• Hair loss
• Stomach pain
• Eye disorder
• Increased thirst
• Arrhythmia (irregular heartbeats)
• Nail disorder

Introduction :

Cycloxan 1 Injection is used in the treatment of various types of cancers of blood, breast, lung, ovaries and soft tissues. It can be administered alone or occasionally in conjunction with other drugs as part of chemotherapy.

It is administered carefully by a licenced medical expert as a drip or infusion vein. Your doctor will determine the appropriate dosage and frequency of administration for you. This is based on the condition you are being treated for and is subject to change. You should follow your doctor's instructions to the letter. It can have potentially dangerous negative effects if taken improperly or in excess.It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to both male and female to use reliable contraception during the treatment.

The most common side effects of this medicine include vomiting, allergic reaction, nausea, mouth sore, and hair loss.  If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Infections can sometimes be life-threatening. Regular blood tests are required to monitor your blood cells along with the kidney, liver, and heart function during treatment with this medicine.

Before taking this medicine, tell your doctor if you have severe liver or heart-related problems, or if you are pregnant, or breastfeeding.  Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.


Uses :

Cancer


Benefits :

For cancer:

Cycloxan 1 Injection helps to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. Cycloxan 1 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. You should talk to your doctor about the advantages and disadvantages of this powerful and extremely poisonous medication. While receiving this medication, you should abstain from alcohol consumption and consume lots of water to stay hydrated.


Side Effects :

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

Common side effects of Cycloxan :

• Vomiting
• Allergic reaction
• Nausea
• Mouth sore
• Hair loss
• Stomach pain
• Eye disorder
• Increased thirst
• Arrhythmia (irregular heartbeats)
• Nail disorder

Introduction :

Breast cancer, pancreatic cancer, and non-small cell lung cancer are all treated with the anti-cancer drug Zupaxel 300mg Injection.

It is given as an injection by a qualified medical professional.  Your doctor will determine the appropriate dosage and frequency of administration for you. This is based on the condition you are being treated for and is subject to change. You should follow your doctor's instructions to the letter. It can have potentially dangerous negative effects if taken improperly or in excess. The benefits might not become apparent to you for a few weeks or months, but you shouldn't stop taking it until your doctor instructs you to.

This medication frequently causes nausea, vomiting, and weakness as adverse effects. Serious side effects like hand and lip swelling, hair loss, and weight gain are also possible. Your doctor might advise taking additional medicine in addition to this to lessen these negative effects. But if you experience unusual bleeding or bruises, a sore throat, oral ulcers, or a high temperature, call your doctor right once (fever). Your blood's red and white blood cell counts could drop as a result of this medication, making you more susceptible to infections. You must have routine blood tests to monitor the health of your liver and blood cells.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.


Uses :

Breast cancer

Non-small cell lung cancer

Pancreatic cancer


Side Effects :

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

Common side effects of Zupaxel :

• Nausea
• Vomiting
• Weakness
• Low blood platelets
• Rash
• Upper respiratory tract infection
• Urinary tract infection
• Bleeding
• Anemia (low number of red blood cells)
• Flushing (sense of warmth in the face, ears, neck and trunk)
• Hair loss
• Decreased blood pressure
• Peripheral neuropathy (tingling and numbness of feet and hand)
• Diarrhea
• Decreased white blood cell count (neutrophils)

Introduction :

Endoxan 1 Injection is used in the treatment of various types of cancers of blood, breast, lung, ovaries and soft tissues. It can be administered alone or occasionally in conjunction with other drugs as part of chemotherapy.

It is administered carefully by a licenced medical expert as a drip or infusion vein. Your doctor will determine the appropriate dosage and frequency of administration for you. This is based on the condition you are being treated for and is subject to change. You should follow your doctor's instructions to the letter. It can have potentially dangerous negative effects if taken improperly or in excess.It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. It makes contraceptive pills less effective, so it advised to both male and female to use reliable contraception during the treatment.

The most common side effects of this medicine include vomiting, allergic reaction, nausea, mouth sore, and hair loss.  If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. Infections can sometimes be life-threatening. Regular blood tests are required to monitor your blood cells along with the kidney, liver, and heart function during treatment with this medicine.

Before taking this medicine, tell your doctor if you have severe liver or heart-related problems, or if you are pregnant, or breastfeeding.  Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works.


Uses :

Cancer


Benefits :

For cancer:

Endoxan 1 Injection helps to treat certain kinds of cancer. It may be used alone or in combination with other medicines to treat cancer in various parts of the body. Endoxan 1 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. You should talk to your doctor about the advantages and disadvantages of this powerful and extremely poisonous medication. While receiving this medication, you should abstain from alcohol consumption and consume lots of water to stay hydrated.


Side Effects :

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

Common side effects of Endoxan :

• Vomiting
• Allergic reaction
• Nausea
• Mouth sore
• Hair loss
• Stomach pain
• Eye disorder
• Increased thirst
• Arrhythmia (irregular heartbeats)
• Nail disorder

Product introduction

Vinbicel 10 Injection is an anti-cancer medication used in the treatment of breast cancer and non-small cell lung cancer.

It is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. 

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. Men are advised to seek guidance and counselling on sperm conservation before taking this therapy.

Uses of Vinbicel Injection

Breast cancer

Non-small cell lung cancer

Benefits of Vinbicel Injection

In Breast cancer

Vinbicel 10 Injection helps to treat breast cancer and it may be used alone or in combination with other medicines or treatment modalities like chemotherapy. It relieves the symptoms of breast cancer such as breast lumps, bloody discharge from nipples or changes in the shape or texture of the breast. Vinbicel 10 Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. Discuss with your doctor if any of the side effects bother you.

In Non-small cell lung cancer

Non-small cell lung cancer is one of the major kinds of lung cancer and it affects both smokers as well as non-smokers. Vinbicel 10 Injection helps treat non-small cell lung cancer and may be given alone or in combination with other medicines. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side effects of Vinbicel Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Vinbicel

Nausea

Vomiting

Weakness

Fatigue

Hair loss

Low blood platelets

Increased liver enzymes

Fever

Anemia (low number of red blood cells)

Bleeding

Constipation

Alcohol

It is not known whether it is safe to consume alcohol with Vinbicel 10 Injection.

Pregnancy

Vinbicel 10 Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks.

Breast feeding

Vinbicel 10 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

Vinbicel 10 Injection does not usually affect your ability to drive.

Kidney

Vinbicel 10 Injection is safe to use in patients with kidney disease. No dose adjustment of Vinbicel 10 Injection is recommended.

However, talk to your doctor if you have any underlying kidney disease.

Liver

Vinbicel 10 Injection should be used with caution in patients with liver disease. Dose adjustment of Vinbicel 10 Injection may be needed.

Regular monitoring of liver function tests is advised while these patients are taking this medicine.