Corsantrum Technology

Jakavi Tablets 20 mg

PRODUCT INTRODUCTION

Jakavi 20mg Tablet is used in the treatment of chronic idiopathic myelofibrosis and Polycythemia vera.

Jakavi 20mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, dizziness, low platelet count are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, kidney and lipid levels.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

USES OF JAKAVI TABLET

Polycythemia vera

Chronic idiopathic myelofibrosis

BENEFITS OF JAKAVI TABLET

In Polycythemia vera

Polycythemia vera is a type of blood cancer that causes excessive production of red blood cells. This may lead to blood clot formation and lead to other serious health issues. Jakavi 20mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

In Chronic idiopathic myelofibrosis

Chronic idiopathic myelofibrosis is a long-term problem that causes fibrous, or scar, tissue to form in the bone marrow. The scarring means the bone marrow can't work normally and produces fewer red blood cells and usually too many white blood cells. Jakavi 20mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. You may experience some bothersome side effects. Discuss with your doctor if you have any doubts.

SIDE EFFECTS OF JAKAVI TABLET

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Jakavi

Headache

Dizziness

Low blood platelets

Anemia (low number of red blood cells)

HOW TO USE JAKAVI TABLET

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Jakavi 20mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

HOW JAKAVI TABLET WORKS

Jakavi 20mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Uses

This medication is used to treat certain bone marrow disorders (myelofibrosis, polycythemia vera). It works by blocking your body from producing substances called growth factors. Growth factors cause cells to grow and divide, and cause the blood cell and spleen problems found in these disorders. Ruxolitinib belongs to a class of drugs known as kinase inhibitors. Though not a cure for these disorders, ruxolitinib may help with some of the symptoms, including abdominal discomfort, pain under left ribs, early feelings of fullness from meals, night sweats, itching, and bone/muscle pain.Ruxolitinib is also used to treat a certain problem that may occur after certain stem cell or bone marrow transplants (graft versus host disease). It works by weakening your body's defense system (immune system).

How to use Ruxolitinib Tablet

Read the Patient Information Leaflet if available from your pharmacist before you start taking ruxolitinib and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

The dosage is based on your medical condition, lab tests, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

Avoid eating grapefruit or drinking grapefruit juice while using this medication unless your doctor or pharmacist says you may do so safely. Grapefruit can increase the chance of side effects with this medicine.

Side Effects

Dizziness, diarrhea, headache, weight gain, or gas may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly.

People using this medication may have serious side effects. However, you have been prescribed this drug because your doctor has judged that the benefit to you is greater than the risk of side effects. Careful monitoring by your doctor may decrease your risk.

Tell your doctor right away if you have any serious side effects, including: unusual tiredness, easy bleeding/bruising, unusual skin changes.

This medication may lower your ability to fight infections. This may make you more likely to get a serious (rarely fatal) infection or make any infection you have worse. Tell your doctor right away if you have any signs of infection (such as sore throat that doesn't go away, fever, chills, cough, painful skin rash/blisters).

This medication may also increase your risk of getting a rare but very serious (sometimes fatal) brain infection (progressive multifocal leukoencephalopathy-PML). Get medical help right away if any of these rare but very serious side effects occur: clumsiness, loss of coordination, weakness, sudden change your thinking (such as confusion, difficulty concentrating), difficulty moving your muscles, problems with speech, seizure, vision changes.

Overdose

Notes

Do not share this medication with others.

Lab and/or medical tests (such as complete blood counts, cholesterol/triglyceride levels, skin exams) should be done before you start taking this medication and while you are taking it. Keep all medical and lab appointments. Consult your doctor for more details.

Missed Dose

If you miss a dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Jakavi Tablets 5 mg

PRODUCT INTRODUCTION

Jakavi 5Mg Tablet is used in the treatment of chronic idiopathic myelofibrosis and Polycythemia vera.

Jakavi 5mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, dizziness, low platelet count are some common side effects of this medicine. This medicine may reduce the number of blood cells (decrease red blood) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, kidney and lipid levels.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

USES OF JAKAVI TABLET

Polycythemia vera

Chronic idiopathic myelofibrosis

BENEFITS OF JAKAVI TABLET

In Polycythemia vera

Polycythemia vera is a type of blood cancer that causes excessive production of red blood cells. This may lead to blood clot formation and lead to other serious health issues. Jakavi 5mgTablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is an effective, yet very toxic medicine and you should discuss the risks and benefits with your doctor. Avoid drinking alcohol or smoking while having this treatment and drink plenty of water to stay hydrated.

In Chronic idiopathic myelofibrosis

Chronic idiopathic myelofibrosis is a long-term problem that causes fibrous, or scar, tissue to form in the bone marrow. The scarring means the bone marrow can't work normally and produces fewer red blood cells and usually too many white blood cells. Jakavi 5mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. You may experience some bothersome side effects. Discuss with your doctor if you have any doubts.

SIDE EFFECTS OF JAKAVI TABLET

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Jakavi

Headache

Dizziness

Low blood platelets

Anemia (low number of red blood cells)

HOW TO USE JAKAVI TABLET

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Jakavi 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

HOW JAKAVI TABLET WORKS

Jakavi 5mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.